SCIENTIFIC PROGRAMME

The 115th annual meeting programme features five themed, co-sponsored symposia, including two named lectures, plenary presentations, oral scientific abstracts and flash poster presentations.

Please refer to the ‘speaker page’ of the website to read the biographies of each of the eminent professors who will be leading this years’ programme.

Please note the Programme may be subject to change.

The 115th Annual Meeting of the Association of Physicians of Great Britain & Ireland has been approved by the Federation of the Royal Colleges of Physicians of the United Kingdom for 10 category 1 (external) CPD credit(s). A certificate of attendance will be issued upon completion of the AoP’s post meeting delegate survey.

The 2022 Annual Meeting Programmes

  1. Thursday 10 March 2022 - Early Career Researchers Workshop 09:15 - 12:25

      Thursday 10 March 2022
    09:15 – 09:20 Introduction & Welcome
    AoP President: Professor Seamas Donnelly, Professor of Medicine, Discipline Head, Clinical Medicine
    09:20 – 10:05 Session 1: Becoming Established as a Clinical Academic
    Three senior clinician scientists share their experience in writing successful grant applications and navigating the early post-doctoral world
    09:20 – 09:35: Professor David McAllister, Professor of Clinical Epidemiology and Medical Informatics, Institute of Health & Wellbeing at University of Glasgow and 09:35 – 09:50: Professor Charlotte Summers, University Professor of Intensive Care Medicine and Director of Clinical Academic Training, University of Cambridge and 09:50 – 10:05: Professor David O’Dwyer, Assistant Professor, Pulmonary Clinic, Taubman Center, Michigan (on-line)
    10:05 – 10:45 Session 2: Engaging the Public and Patients in Science
    10:05 – 10:25: Professor Luke O’Neill, Professor Chair of Biochemistry, Trinity College Dublin and 10:25 – 10:45: Professor Ursula Fearon, Professor of Molecular Rheumatology, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin (on-line)
    10:45 – 11:15 Break
    11:15 – 11:30 Session 3: Balancing Clinical and Academic Demands Throughout Your Career
    Professor Richard Wilson, Professor of Gastrointestinal Oncology, Institute of Cancer Sciences, University of Glasgow. Honorary Consultant in Medical Oncology, Beatson West of Scotland Cancer Centre.
    11:30 – 11:50 Session 4: Funding Schemes for Clinicians
    Dr Maja Wallberg, Senior Research Manager, Discovery Research, Wellcome Trust
    11:50 – 12:25 Session 5: The Bigger Picture – Priority Research Areas from the DHSC
    Professor Lucy Chappell, UK DHSC Chief Scientific Advisor and Consultant Obstetrician

  2. Thursday 10 March 2022 - Main Meeting Programme from 12:30
    Thursday 10 March 2022
    09:15-12:30 Early Career Researchers Workshop
    12:30-13:25 Lunch & Poster Viewing
    13:25-13:30 Welcome ~ 115th Annual Meeting
    AoP Honorary Secretary: Professor Christian Delles, Professor and Consultant Physician at the Institute for Cardiovascular and Medical Sciences, University of Glasgow
    AoP President: Professor Seamas Donnelly, Professor of Medicine, Discipline Head, Clinical Medicine, & Professor Linda Doyle, Provost, Trinity College Dublin
    13:30-15:10 SYMPOSIUM #1
    Changing the Course of Ageing and Neurodegeneration ~ in partnership with The American Society for Clinical Investigation

    Joint Chairs: Professor Lucy Chappell, Chief Scientific Advisor, Department of Health & Social Care & Professor Hossein Ardehali, President, The American Society for Clinical Investigation
    13:30-13:35 Welcome from The American Society for Clinical Investigation
    Professor Hossein Ardehali, President, The American Society for Clinical Investigation
    13:35-14:00 Plenary “Heart Brain Connections and Ageing”
    Professor Rose Anne Kenny, Professor of Medical Gerontology, Trinity College Dublin. Director of the Falls & Blackout Unit, St James’s Hospital, Dublin. Director. Mercer’s Institute for Successful Ageing.
    14:00-14:30 Oral Presentations x 3
    14:30-14:55 The Osler Lecture “New Genetic Therapies for Neurodegenerative Diseases”
    Professor Sarah Tabrizi , Director, Huntington’s Disease Centre, University College London (UCL). Joint Head of Department, Neurodegenerative Disease, Queen Street Institute of Neurology, UCL. Principal Investigator, UK Dementia Research Institute. Honorary Consultant Neurologist, National Hospital for Neurology & Neurosurgery.
    14:55-15:10 Q&A
    15:10-15:30 Break
    15:30-17:30 SYMPOSIUM #2
    Diet, the Microbiome and Disease – Time to Take Note? ~ in partnership with Science Translational Medicine

    Joint Chairs: Professor Seamas Donnelly, Professor of Medicine, Discipline Head, Clinical Medicine, Trinity College Dublin and Dr Orla Smith, Editor, Science Translational Medicine
    15:30-15:35 Welcome from Science Translational Medicine
    Dr Orla Smith, Editor, Science Translational Medicine
    15:35-16:00 Plenary “Host Microbiome Interactions in Health and Disease”
    Professor Eran Elinav, Principal Investigator, Weizmann Institute, Israel
    16:00-16:30 Oral Presentations x3
    16:30-16:55 Plenary “Translating Microbiome Science: challenges and opportunities ”
    Professor Fergus Shanahan, Emeritus Professor of Medicine, University College, Cork
    16:55-17:10 Q&A
    17:10-17:30 Flash Posters
    17:30-18:00 Meet Our Partners, Poster Viewing
    18:00-18:30 Free Time
    18:30-19:30 Networking Reception (included in registration fee)
    19:30-23:00 Networking Dinner (provided by AoP as part of registration fee)
  3. Friday 11 March 2022 Main Meeting Programme
    Friday 11 March 2022
    09:00-10:40 SYMPOSIUM #3
    New Ways to Control Inflammation and Healing ~ in partnership with The British Society of Immunology

    Joint Chairs: Professor Arne Akbar, Associate of the Institute of Healthy Ageing, Professor of Immunology at University College London & President of the British Society of Immunology, and Professor Alan Irvine, Professor of Dermatology, Trinity College Dublin
    09:00-09:05 Welcome from The British Society of Immunology
    Professor Arne Akbar, Associate of the Institute of Healthy Ageing, Professor of Immunology at University College London & President of the British Society of Immunology
    09:05-09:30 Plenary “Immunometabolism in a Translational Medicine World”
    Professor Luke O’Neill ~ Professor (Chair of Biochemistry), Trinity College Dublin
    09:30-10:00 Oral Presentations x3
    10:00-10:25 Plenary “Next Generation Immunogenomics to Understand Health and Disease”
    Professor Muzlifah Haniffa, Wellcome Trust Senior Research Fellow in Clinical Science and Professor of Dermatology and Immunology, Newcastle University
    10:25-10:40 Q&A
    10:40-11:00 Break
    11:00-12:30 SYMPOSIUM #4
    Oral Presentations

    Joint Chairs: Professor Richard Wilson, Professor of Gastro-Intestinal Oncology, Institute of Cancer Sciences in the University of Glasgow, Professor of Gastrointestinal Oncology and Honorary Consultant in Medical Oncology, Beatson West of Scotland Cancer Centre and, Professor Sir Munir Pirmohamed, David Weatherall Chair of Medicine and NHS Chair of Pharmacogenetics, Director, Centre for Drug Safety Science and Wolfson Centre for Personalised Medicine, Director, HDR UK North Institute of Systems, Molecular and Integrative Biology (ISMIB) University of Liverpool
    11:00-12:00 Welcome by Chairs
    11:00-12:00 Oral Presentations x6
    12:00-12:20 Flash Posters
    12:20-12:30 AoP Fellows Inauguration
    Chair: Professor Colin Dayan (TBC), Professor of Clinical Diabetes and Metabolism, Cardiff University School of Medicine
    12:30-13:30 Lunch & Poster Viewing
    13:30-15:20 SYMPOSIUM #5
    COVID-19 – What Lessons Have we Learned?~ in partnership with Nature Medicine

    Joint Chairs: Professor Charlotte Summers, University Professor of Intensive Care Medicine and Director of Clinical Academic Training, University of Cambridge & Dr Jennifer Sargent, Deputy Editor, Nature Medicine
    13:30-13:35 Welcome from Nature Medicine
    Dr Jennifer Sargent, Deputy Editor, Nature Medicine
    13:35-14:00 Plenary “2 years of discovery – what we’ve learned about critical Covid-19”
    Professor Kenneth Baillie, Professor of Experimental Medicine, The Roslin Institute, University of Edinburgh
    14:00-14:30 Oral Presentations x3
    14:30-14:55 The George Griffin Lecture “Medical science in a crisis: building back better after COVID-19”
    Professor Sir Peter Horby, Director, Pandemic Sciences Centre, Professor of Emerging Infectious Diseases and Global Health. Former Director of the Oxford University Clinical Research Unit in Hanoi, Vietnam
    14:55-15:10 Q&A
    15:10-15:20 Prizes and Close

Speakers

Professor Fergus Shanahan

Position: Emeritus Professor of Medicine at University College Cork, Ireland
Categories: AoP Speaker

Thursday 10 March

“Translating Microbiome Science: challenges and opportunities”

Symposium – Diet, the Microbiome and Disease – Time to Take Note?

Emeritus Professor of Medicine at University College Cork, Ireland

Fergus Shanahan, MD, DSc, MRIA is Emeritus Professor of Medicine at University College Cork, Ireland. He is a clinician, a teacher, a researcher, an entrepreneur, and an author. He graduated from University College Dublin, trained in immunology at McMaster University, Canada and in gastroenterology at University of California Los Angeles (UCLA). He founded one of the world’s first microbiome research centres (APC Microbiome Ireland) and is co-founder of three successful start-up companies. He is a former president of the Irish Society of Gastroenterology. He was recently listed in the top 1% of highly cited scientists by Clarivate. He has received many awards for contributions to medical science and the medical humanities, including a gold medal from the Royal Irish Academy. He has numerous patents, has published over 580 scientific papers, and has co-written or edited several books, one of which won the BMA book award for gastroenterology. His latest book, The Language of Illness, is published by Liberties Press, Dublin http://www.libertiespress.com/shop/the-language-of-illness.

Professor Fergus Shanahan

Emeritus Professor of Medicine at University College Cork, Ireland

Thursday 10 March “Translating Microbiome Science: challenges and opportunities” Symposium...

Professor Rose Anne Kenny

Position: Medical Gerontology at Trinity College Dublin
Categories: AoP Speaker

Thursday 10 March

“Heart Brain Connections and Ageing”

Symposium – Changing the Course of Ageing and Neurodegeneration

Professor of Medical Gerontology at Trinity College Dublin, Director of the Falls and Blackout Unit at St. James’s Hospital Dublin and Director of the new Mercer’s Institute for Successful Ageing

Professor Rose Anne Kenny holds the Chair of Medical Gerontology at Trinity College Dublin and is the Founder and Principal Investigator of The Irish Longitudinal Study on Ageing (TILDA), Ireland’s flagship research project in ageing. Professor Kenny’s research focuses on the causes and consequences of neurocardiovascular ageing. In 2016, she launched a new 120 bedded clinical research institute on the site of Ireland’s largest teaching hospital (St. James’s Hospital), where she is Director of a state of the art dedicated falls and syncope facility – the largest such clinical model in Europe and an exemplar for the newly proposed Academic Health Sciences Centre (AHSC) at St James’s Hospital and Trinity College Dublin. Prior to her present appointments, she held the Chair of Cardiovascular Research at the University of Newcastle Upon Tyne, UK, where she was Head of the Academic Department of Medical Gerontology for 12 years. Professor Kenny has held a number of senior positions including, Chair of the American Geriatric Society: Falls Prevention Guidelines (2001 & 2011), Chair of the European Cardiac Society/ European Heart Rhythm Association Guidelines for Syncope units (2015), Member of the European Cardiac Society (ECS) Syncope Guidelines Taskforce 2018, Board Member of the EU H2020 Advisory Group for Societal Challenge and Co-Chair of the working group “Transforming the Future of Ageing” lead by the Scientific Advisory Policy by European Academies (SAPEA). She is also Advisor to the Irish Government for Jobs, Enterprise and Innovation and the Irish Citizens’ Assembly on Ageing. She has received a number of international awards and has published widely, authoring over 600 publications to date. In 2014, she was the first female physician to be elected as a Member of the Royal Irish Academy (MRIA) and is a Fellow of the Royal College of Physicians of Edinburgh, London and Ireland (FRCPEdin, FRCP & FRCPI), a Fellow of Trinity College Dublin (FTCD) and newly appointed Honorary Fellow of the Faculty of Public Health Medicine (FFPHMI (Hon)).

Professor Rose Anne Kenny

Medical Gerontology at Trinity College Dublin

Thursday 10 March “Heart Brain Connections and Ageing” Symposium –...

Professor Eran Elinav

Position: Department of Immunology, Weizmann Institute of Science
Categories: AoP Speaker

Thursday 10 March

“Host Microbiome Interactions in Health and Disease”

Symposium – Diet, the Microbiome and Disease – Time to Take Note?

Principal Investigator, Weizmann Institute of Science

Prof. Eran Elinav, M.D., Ph.D. is a professor at the Department of Immunology, Weizmann Institute of Science, and since 2019 the director of the cancer-microbiome division, at the Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany. His labs at the Weizmann Institute and DKFZ focus on deciphering the molecular basis of host-microbiome interactions and their effects on health and disease, with a goal of personalizing medicine and nutrition. Dr. Elinav completed his medical doctor’s (MD) degree at the Hebrew University of Jerusalem Hadassah Medical Center summa cum laude, followed by a clinical internship, residency in internal medicine, and a physician-scientist position at the Tel Aviv Medical Center Gastroenterology institute. He received a PhD in immunology from the Weizmann Institute of Science, followed by a postdoctoral fellowship at Yale University School of Medicine. Dr. Elinav has published more than 150 publications in leading peer-reviewed journals, including major recent discoveries related to the effects of host genetics, innate immune function and environmental factors, such as dietary composition and timing, on the intestinal microbiome and its propensity to drive multi-factorial disease. His honors include multiple awards for academic excellence including the Claire and Emmanuel G. Rosenblatt award from the American Physicians for Medicine (2011), the Alon Foundation award (2012), the Rappaport prize for biomedical research (2015) the Levinson award for basic science research (2016), and the Landau prize (2018). Since 2016 he is a senior fellow at the Canadian Institute For Advanced Research (CIFAR), since 2017 he is an elected member, European Molecular Biology Organization (EMBO) and an international scholar at the Howard Hughes Medical Institute (HHMI) and the Bill & Melinda Gates Foundation.

Professor Eran Elinav

Department of Immunology, Weizmann Institute of Science

Thursday 10 March “Host Microbiome Interactions in Health and Disease”...

Professor Sarah Tabrizi

Position: Director of the University College London (UCL) Huntington’s Disease (HD) Centre
Categories: AoP Speaker

Thursday 10 March

The Osler Lecture – New Genetic Therapies for Neurodegenerative Diseases

Symposium – Changing the Course of Ageing and Neurodegeneration

Director of the University College London (UCL) Huntington’s Disease (HD) Centre

Sarah Tabrizi is Director of the UCL Huntington’s Disease (HD) Centre, Joint Head of Department Neurodegenerative Disease at the UCL Queen Square Institute of Neurology, a Principal Investigator at the UK Dementia Research Institute, and Honorary Consultant Neurologist at the National Hospital for Neurology and Neurosurgery. She graduated in Biochemistry, then studied Medicine at the University of Edinburgh where she was awarded the 1992 Leslie Gold Medal for the most distinguished medical graduate. Sarah undertook her PhD and trained as an independent scientist at UCL, establishing a large basic bench science and translational research team focussed on finding disease modifying therapies for HD. She was PI on the first successful phase 1/2b trial of an antisense oligonucleotide (NEJM 2019) and currently serves on several SABs advising industry on the development of potential gene targeting and nucleic acid therapies for HD. Sarah has published over 300 peer-reviewed research papers. In 2014 she was elected as a Fellow of the UK Academy of Medical Sciences. In 2017 she received the seventh Leslie Gehry Brenner Prize for Innovation in Science awarded by the Hereditary Disease Foundation. In 2018 she received the Cotzias Award from the Spanish Society of Neurology, and in 2019 the Yahr Award at the World Congress for Neurology and the Alexander Morison Medal from the Royal College of Physicians of Edinburgh.

Professor Sarah Tabrizi

Director of the University College London (UCL) Huntington’s Disease (HD) Centre

Thursday 10 March The Osler Lecture – New Genetic Therapies...

Professor Sir Peter Horby

Position: Director, Pandemic Sciences Centre
Categories: AoP Speaker

Friday 11 March

The George Griffin Lecture

“Medical science in a crisis: building back better after COVID-19”

COVID-19 – What Lessons Have We Learned?

Professor of Emerging Infectious Diseases and Global Health
University of Oxford

Peter trained in medicine at University College London and went on to specialise in emerging and epidemic prone infectious diseases. Over the last 20 years he has led research on a wide range of emerging and epidemic infections, including SARS, avian influenza, Ebola, Lassa fever, plague and COVID-19.

He lived and worked in Southeast Asia for 11 years, working initially for the World Health Organisation in Vietnam before establishing a research centre at the National Hospital for Tropical Diseases in Hanoi in 2006. The research centre is still flourishing and in 2016 he was awarded the People’s Health Medal by the Government of Vietnam.
Peter returned to the United Kingdom in 2014 to set up an epidemic disease research group at the University of Oxford and is Director of the recently established Pandemic Sciences Centre. He is also Executive Director of the International Severe Acute Respiratory and emerging Infections Consortium (ISARIC), a consortium of 53 international, national and local research networks whose research activities span 134 countries worldwide, and is also the coordinator of the African coaLition for Epidemic Research, Response and Training (ALERRT), a sub-Saharan Africa consortium on clinical research for epidemic-prone infections, with 21 partner institutions and representation across 25 sub-Saharan Africa countries. He is a member of the UK Government Scientific Advisory Group for Emergencies (SAGE) and chairs the New and Emergency Respiratory Virus Threats Advisory Group.

Peter co-leads the RECOVERY trial of treatments for COVID-19, which has randomised over 42,000 participants and evaluated 13 drugs.
He was knighted for Services to Medical Research in the 2021 Queen’s Birthday honours list.

Professor Sir Peter Horby

Director, Pandemic Sciences Centre

Friday 11 March The George Griffin Lecture “Medical science in...

Professor Muzlifah Haniffa

Position: Professor of Dermatology and Immunology, Newcastle University
Categories: AoP Speaker

Friday 11 March

“Next Generation Immunogenomics to Understand Health and Disease”

Symposium – New Ways to Control Inflammation and Healing

Wellcome Trust Senior Research Fellow in Clinical Science and Professor of Dermatology and Immunology, Newcastle University

Muzlifah Haniffa is a Wellcome Trust Senior Research Fellow, Consultant Dermatologist at Newcastle University and Associate Faculty, Cellular Genetics, Wellcome Sanger Institute. She graduated from medical school in Cardiff, trained as a junior doctor in Cambridge and received her dermatology specialist training in Newcastle.
Muzlifah is a Fellow of the Academy of Medical Sciences (2020) and the recipient of the Academy of Medical Sciences Foulkes Foundation Medal (2019) and the European Federation of Immunological Societies ACTERIA Prize in Immunology and Allergology (2018). She is a leading member of the Human Cell Atlas initiative and pioneered the application of single cell genomics to decode the developing human immune system, and the human skin in health and disease.

Professor Muzlifah Haniffa

Professor of Dermatology and Immunology, Newcastle University

Friday 11 March “Next Generation Immunogenomics to Understand Health and...

Professor Luke O’Neill

Position: Professor of Biochemistry in the School of Biochemistry and Immunology
Categories: AoP Speaker, ECR Speaker

Prof Luke O’Neill is Professor of Biochemistry in the School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute at Trinity College Dublin, Ireland. He is a world expert on innate immunity and inflammation. His main research interests include Toll-like receptors, Inflammasomes and Immunometabolism. He is listed by Thompson Reuters/ Clarivates in the top 1% of immunologists in the world, based on citations per paper. Professor O’Neill is co-founder of Sitryx, which aims to develop new medicines for inflammatory diseases. Another company he co-founded, Inflazome was recently acquired by Roche.

He was awarded the Royal Dublin Society / Irish Times Boyle Medal for scientific excellence, the Royal Irish Academy Gold Medal for Life Sciences, The Society for Leukocyte Biology (SLB) Dolph O. Adams award, the European Federation of Immunology Societies Medal and in 2018 the Milstein Award of the International Cytokine and Interferon Society. He is a member of the Royal Irish Academy, EMBO (European Molecular Biology Organisation) and a Fellow of the Royal Society.

Professor Luke O’Neill

Professor of Biochemistry in the School of Biochemistry and Immunology

Prof Luke O’Neill is Professor of Biochemistry in the School...

Professor Kenneth Baillie

Position: Professor of Experimental Medicine, The Roslin Institute, University of Edinburgh
Categories: AoP Speaker

Friday 11 March

“2 Years of Discovery – What We’ve Learned About Critical Covid-19”

COVID-19 – What Lessons Have We Learned?

Professor of Experimental Medicine, The Roslin Institute, University of Edinburgh

Kenneth Baillie graduated from the University of Edinburgh with a BSc(Hons) in Physiology in 1999 and MBChB in 2002. He completed basic training in medicine in Glasgow, and in anesthesia in Edinburgh. During this time he led a series of high altitude research projects in Bolivia, and founded a high-altitude research charity, Apex. He was appointed as a clinical lecturer on the ECAT (Edinburgh Clinical Academic Track) at the University of Edinburgh in 2008, and completed a Wellcome Trust-funded PhD in statistical genetics in 2012. He was awarded a Wellcome-Beit Prize Intermediate Clinical Fellowship in 2013. He led a global consensus on harmonisation of research studies in outbreaks for the International Severe Acute Respiratory Infection Consortium (ISARIC), and worked with WHO on H1N1 influenza, MERS, and Ebola. After completing clinical training in 2014 he worked as a visiting scientist at the Broad Institute of Harvard and MIT, before returning to the Roslin Institute, University of Edinburgh to establish a research program in translational applications of genomics in critical care medicine. He works as a consultant in the intensive care unit at the Royal Infirmary, Edinburgh. During the Covid outbreak in 2020-21, he led the UK-wide GenOMICC and ISARIC4C studies, and contributed to the design and delivery of the RECOVERY trial. He discovered new biological mechanisms underlying critical illness in Covid, and contributed to the discovery of effective drug treatments to reduce mortality.

Professor Kenneth Baillie

Professor of Experimental Medicine, The Roslin Institute, University of Edinburgh

Friday 11 March “2 Years of Discovery – What We’ve...